Auto Trader atop on upbeat margin outlook
AstraZeneca soars as it ups profit outlook
Flutter drops, sees FY earnings at bottom of range
FTSE 100 down 0.1, FTSE 250 off 0.3

Nov 9 Reuters UK39;s FTSE 100 fell on Thursday, hurt by a drop in shares of Flutter after a dour forecast, with investors awaiting comments from U.S. Federal Reserve Chair Jerome Powell to gauge the path for global interest rates.

The FSTE 100 slid 0.1 and headed for its fourth session of decline in six.

Flutter dropped 9.5, dragging the travel and leisure index to over a week39;s low after the online betting company said it expects fullyear earnings, excluding the nascent U.S. market, at the bottom of its previous forecast range.

The U.S. has been the big opportunity for Flutter for some time, and remains so, but today39;s warning is a reminder that this is a bigger beast, and if everything is not working in its favour, the consequences can be dire for investors, said Russ Mould, investment director at AJ Bell.

AstraZeneca was among the top gainers on FTSE 100, jumping 2.7 after the drugmaker raised its annual core profit outlook, buoyed by strong demand for its oncology and rare blood disorder drugs.

Taylor Wimpey soared 2.0 after the homebuilder forecast annual operating profit at the topend of its previous outlook range.

A survey showed that Britain saw some of the most widespread falls in house prices since 2009 last month, but the declines were at a slightly slower pace than in the…